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Sandro De Falco Selected Research

Pathologic Neovascularization

4/2021Prolyl 3-Hydroxylase 2 Is a Molecular Player of Angiogenesis.
1/2020Oral Delivery of a Tetrameric Tripeptide Inhibitor of VEGFR1 Suppresses Pathological Choroid Neovascularization.
2/2018Placental growth factor and its potential role in diabetic retinopathy and other ocular neovascular diseases.
1/2018Targeting VEGF receptors with non-neutralizing cyclopeptides for imaging applications.
1/2018Full Functional Knockout of Placental Growth Factor by Knockin with an Inactive Variant Able to Heterodimerize with VEGF-A.
7/2015The vascular endothelial growth factors and receptors family: Up to now the only target for anti-angiogenesis therapy.
4/2014Epigenetic control of hypoxia inducible factor-1α-dependent expression of placental growth factor in hypoxic conditions.
1/2013Bioassay-guided isolation of proanthocyanidins with antiangiogenic activities.
12/2012Inhibition of choroidal and corneal pathologic neovascularization by Plgf1-de gene transfer.
6/2011The biflavonoid amentoflavone inhibits neovascularization preventing the activity of proangiogenic vascular endothelial growth factors.
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Sandro De Falco Research Topics

Disease

16Neoplasms (Cancer)
12/2020 - 08/2002
13Pathologic Neovascularization
04/2021 - 01/2004
7Choroidal Neovascularization
04/2021 - 04/2009
7Inflammation (Inflammations)
10/2019 - 03/2008
5Ischemia
04/2021 - 08/2002
4Neoplasm Metastasis (Metastasis)
05/2017 - 03/2008
3Macular Degeneration (Age-Related Maculopathy)
01/2021 - 01/2016
3Hypoxia (Hypoxemia)
05/2017 - 04/2014
3Arthritis (Polyarthritis)
01/2010 - 01/2004
2Diabetic Retinopathy (Retinopathy, Diabetic)
01/2021 - 02/2018
2Retinal Diseases
01/2021 - 02/2018
2Blindness (Hysterical Blindness)
01/2020 - 12/2012
2Parkinson Disease (Parkinson's Disease)
01/2020 - 08/2010
2Macular Edema
10/2019 - 11/2017
2Colorectal Neoplasms (Colorectal Cancer)
01/2016 - 04/2015
2Rheumatoid Arthritis
03/2015 - 02/2009
2Carcinoma (Carcinomatosis)
06/2011 - 01/2011
2Experimental Arthritis
01/2010 - 02/2009
1Pathologic Processes
01/2021
1Retinopathy of Prematurity (Retrolental Fibroplasia)
01/2021
1Retinal Vein Occlusion
02/2018
1Vascular Diseases (Vascular Disease)
02/2018
1Glioma (Gliomas)
05/2017
1Corneal Neovascularization
01/2016
1Fibrosarcoma
01/2016
1Autoimmune Diseases (Autoimmune Disease)
01/2016
1Ulcer
01/2015
1T-Cell Leukemia (Leukemia, T Cell)
03/2014
1Colonic Neoplasms (Colon Cancer)
01/2014
1Teratocarcinoma
01/2013
1Melanoma (Melanoma, Malignant)
06/2011
1Intermittent Claudication
03/2010
1Peripheral Arterial Disease
03/2010
1Hyperplasia
01/2010
1Breast Neoplasms (Breast Cancer)
08/2008
1Body Weight (Weight, Body)
01/2004
1Atherosclerosis
01/2004

Drug/Important Bio-Agent (IBA)

19Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2021 - 08/2002
9Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
02/2018 - 01/2004
5Vascular Endothelial Growth Factor Receptor-1 (fms-Like Tyrosine Kinase)IBA
07/2015 - 03/2008
4Retinaldehyde (Retinal)IBA
04/2021 - 02/2018
3Peptides (Polypeptides)IBA
04/2015 - 01/2010
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
04/2021 - 02/2009
2Vascular Endothelial Growth Factor BIBA
01/2021 - 07/2015
2afliberceptIBA
10/2019 - 11/2017
2Pharmaceutical PreparationsIBA
05/2018 - 01/2014
2Bevacizumab (Avastin)FDA Link
04/2015 - 01/2014
2Collagen Type II (Type II Collagen)IBA
01/2010 - 02/2009
1Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA
04/2021
1LigandsIBA
01/2021
1AntibodiesIBA
12/2020
1SynucleinsIBA
01/2020
1Glucose (Dextrose)FDA LinkGeneric
10/2019
1Prostaglandins FIBA
02/2018
1Oxygen (Dioxygen)IBA
02/2018
1Transcription Factors (Transcription Factor)IBA
05/2017
1Proteins (Proteins, Gene)FDA Link
05/2017
1Intravenous Immunoglobulins (IVIG)FDA Link
01/2016
1Vascular Endothelial Growth Factor Receptor-2 (Vascular Endothelial Growth Factor Receptor 2)IBA
07/2015
1Irinotecan (Camptosar)FDA LinkGeneric
04/2015
1Monoclonal AntibodiesIBA
04/2015
1Nitric Oxide (Nitrogen Monoxide)FDA Link
01/2015
1AntioxidantsIBA
01/2015
1Histones (Histone)IBA
04/2014
1ent-kaurane 15-ketoatractyligenin methyl esterIBA
03/2014
1atractyligenineIBA
03/2014
1ThioredoxinsIBA
03/2014
1nutlin 3IBA
10/2013
1entinostat (MS 275)IBA
01/2013
1Therapeutic UsesIBA
01/2013
1Histone Deacetylase InhibitorsIBA
01/2013
1Angiogenesis InhibitorsIBA
07/2011
1amentoflavoneIBA
06/2011
1Carnitine (L-Carnitine)FDA LinkGeneric
03/2010
1Neuropilin-1IBA
01/2010
1Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA
01/2010
1AutoantibodiesIBA
01/2010
1Toll-Like Receptor 3IBA
04/2009
1Small Interfering RNA (siRNA)IBA
04/2009
1Double-Stranded RNA (RNA, Double Stranded)IBA
04/2009
1Interleukin-6 (Interleukin 6)IBA
02/2009
1Placenta Growth FactorIBA
02/2009
1CytokinesIBA
02/2009
1ErbB Receptors (EGF Receptor)IBA
08/2008
1vandetanib (ZD6474)IBA
08/2008
1Phosphotransferases (Kinase)IBA
08/2008
1Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA
05/2006
1Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
01/2004
1Citrate (si)-Synthase (Synthase, Citrate)IBA
01/2004

Therapy/Procedure

6Lasers (Laser)
04/2021 - 12/2012
5Therapeutics
01/2020 - 08/2010
1Intravitreal Injections
04/2015
1Subcutaneous Injections
01/2010
1Sutures (Suture)
04/2009